Prof. Bernhard Wolfrum

Principal Investigator

Address

85748 Garching

Phone

+49-89-289-10887

Email

bernhard.wolfrum[at]tum.de

Research topics

• cell-chip coupling: recording and stimulation of network activity
• network patterning: microfluidic cell culture
• on-chip neuroscience: lesion and degeneration models
• printing technologies for biohybrid systems and biosensors
• nanoelectrochemical sensor arrays and interfaces

Scientific Approach

• We develop neuroelectronic interfaces using micro- and nanofabrication technologies based on ink-jet printing and lithographical methods. In contrast to classical microfabrication, the use of printing technologies allows rapid prototyping of flexible devices and direct integration of biomaterials.
• We investigate electrochemical redox-cycling techniques for mapping chemical cues from cells in real time.
• We design structured cell networks using microfluidic cell-culture systems to monitor and stimulate network activity at the single-cell level.

Bernstein Projects

Project A4: Monitoring neuronal activity with printed devices. B. Wolfrum (TUM)

Group Members Associated with BCCN

• Philipp Rinklin (PostDoc)
• Troung Ka My Dang (PhD)